We are facing the era of Internet of Things who is rapidly changing the way we work. IoT is a broad collection of digital devices, sensors, intelligent machines who need to communicate with others devices or applications. Cloud technology is a key enabler of the IOT, but IoT is demanding much more. Data coming from these devices need to be managed, processed and analyzed in Real Time. A Real Time answer needs a new concept of technology that extends cloud functionality close to the edge, close where the informations are produced and need to be analyzed. Fog Computing is the technology that enables real-time data processing and analytics. Within then Industry 4.0 paradigm, Fog Computing brings cloud functionality closer to the data enabling Real Time capabilities to integrate Information Technology and Operation Technology in a single and secured platform.